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Research Article

The Ability to Enhance the Solubility of Its Fusion Partners Is an Intrinsic Property of Maltose-Binding Protein but Their Folding Is Either Spontaneous or Chaperone-Mediated

  • Sreejith Raran-Kurussi,

    Affiliation: Protein Engineering Section, Macromolecular Crystallography Laboratory, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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  • David S. Waugh mail

    waughd@mail.nih.gov

    Affiliation: Protein Engineering Section, Macromolecular Crystallography Laboratory, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

    X
  • Published: November 16, 2012
  • DOI: 10.1371/journal.pone.0049589

About the Authors

Sreejith Raran-Kurussi, David S. Waugh
Protein Engineering Section, Macromolecular Crystallography Laboratory, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

Corresponding Author

Email: waughd@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SRK DSW. Performed the experiments: SRK. Analyzed the data: SRK DSW. Wrote the paper: SRK DSW.