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Research Article

Transcriptome Analysis of Renal Ischemia/Reperfusion Injury and Its Modulation by Ischemic Pre-Conditioning or Hemin Treatment

  • Matheus Correa-Costa equal contributor,

    equal contributor Contributed equally to this work with: Matheus Correa-Costa, Hátylas Azevedo

    Affiliation: Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil

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  • Hátylas Azevedo equal contributor,

    equal contributor Contributed equally to this work with: Matheus Correa-Costa, Hátylas Azevedo

    Affiliation: Laboratory of Pediatric Genomics, Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, Brazil

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  • Mariane Tami Amano,

    Affiliation: Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil

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  • Giselle Martins Gonçalves,

    Affiliation: Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil

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  • Meire Ioshie Hyane,

    Affiliation: Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil

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  • Marcos Antonio Cenedeze,

    Affiliation: Laboratory of Clinical and Experimental Immunology, Nephrology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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  • Paulo Guilherme Renesto,

    Affiliations: Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil, Laboratory of Clinical and Experimental Immunology, Nephrology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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  • Alvaro Pacheco-Silva,

    Affiliation: Laboratory of Clinical and Experimental Immunology, Nephrology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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  • Carlos Alberto Moreira-Filho mail,

    niels@icb.usp.br (NOSC); carlos.moreira@hc.fm.usp.br (CAMF)

    Affiliation: Laboratory of Pediatric Genomics, Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, Brazil

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  • Niels Olsen Saraiva Câmara mail

    niels@icb.usp.br (NOSC); carlos.moreira@hc.fm.usp.br (CAMF)

    Affiliations: Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil, Laboratory of Clinical and Experimental Immunology, Nephrology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049569

About the Authors

Matheus Correa-Costa, Mariane Tami Amano, Giselle Martins Gonçalves, Meire Ioshie Hyane, Paulo Guilherme Renesto, Niels Olsen Saraiva Câmara
Laboratory of Transplantation Immunobiology, Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, Brazil
Hátylas Azevedo, Carlos Alberto Moreira-Filho
Laboratory of Pediatric Genomics, Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, Brazil
Marcos Antonio Cenedeze, Paulo Guilherme Renesto, Alvaro Pacheco-Silva, Niels Olsen Saraiva Câmara
Laboratory of Clinical and Experimental Immunology, Nephrology Division, Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MCC HA NOSC. Performed the experiments: MCC HA GMG MTA MAC. Analyzed the data: MCC HA GR NOSC. Contributed reagents/materials/analysis tools: MIH APS CAMF NOSC. Wrote the paper: HA CAMF.