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Research Article

Clinical Utility of the Cryptococcal Antigen Lateral Flow Assay in a Diagnostic Mycology Laboratory

  • Brendan J. McMullan equal contributor mail,

    equal contributor Contributed equally to this work with: Brendan J. McMullan, Catriona Halliday

    brendanoch@yahoo.co.uk

    Affiliations: Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia, Westmead Clinical School, University of Sydney, Westmead, New South Wales, Australia

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  • Catriona Halliday equal contributor,

    equal contributor Contributed equally to this work with: Brendan J. McMullan, Catriona Halliday

    Affiliation: Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia

    X
  • Tania C. Sorrell,

    Affiliations: Sydney Emerging Infections and Biosecurity Institute, University of Sydney, Sydney, New South Wales, Australia, Westmead Millennium Institute, Westmead, New South Wales, Australia

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  • David Judd,

    Affiliation: Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia

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  • Sue Sleiman,

    Affiliation: Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia

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  • Debbie Marriott,

    Affiliation: Department of Microbiology and Infectious Diseases, St. Vincent's Hospital, Sydney, New South Wales, Australia

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  • Tom Olma,

    Affiliation: Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia

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  • Sharon C-A. Chen

    Affiliations: Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia, Sydney Emerging Infections and Biosecurity Institute, University of Sydney, Sydney, New South Wales, Australia, Westmead Millennium Institute, Westmead, New South Wales, Australia

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049541

About the Authors

Brendan J. McMullan, Catriona Halliday, David Judd, Sue Sleiman, Tom Olma, Sharon C-A. Chen
Centre for Infectious Diseases and Microbiology Laboratory Services, Westmead Hospital, Westmead, New South Wales, Australia
Brendan J. McMullan
Westmead Clinical School, University of Sydney, Westmead, New South Wales, Australia
Tania C. Sorrell, Sharon C-A. Chen
Sydney Emerging Infections and Biosecurity Institute, University of Sydney, Sydney, New South Wales, Australia
Tania C. Sorrell, Sharon C-A. Chen
Westmead Millennium Institute, Westmead, New South Wales, Australia
Debbie Marriott
Department of Microbiology and Infectious Diseases, St. Vincent's Hospital, Sydney, New South Wales, Australia

Corresponding Author

Email: brendanoch@yahoo.co.uk

Competing Interests

The authors would like to declare the following funding-related matter: they received the first 500 LFA kits free-of-charge from ABACUS, ALS Australia. The authors declare no other commercial funding or association, including consultancy, patents or products. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: BJM CH TCS DJ SS DM TO SCAC. Performed the experiments: BJM CH DJ SS. Analyzed the data: BJM CH TCS SCAC. Contributed reagents/materials/analysis tools: TO CH SCAC. Wrote the paper: BJM CH TCS SCAC.