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Research Article

Using Phage and Yeast Display to Select Hundreds of Monoclonal Antibodies: Application to Antigen 85, a Tuberculosis Biomarker

  • Fortunato Ferrara,

    Affiliation: Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Leslie A. Naranjo,

    Affiliation: Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Sandeep Kumar,

    Affiliation: Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Tiziano Gaiotto,

    Affiliation: Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

    X
  • Harshini Mukundan,

    Affiliation: Chemistry Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Basil Swanson,

    Affiliation: Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Andrew R. M. Bradbury mail

    amb@lanl.gov

    Affiliation: Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0049535

About the Authors

Fortunato Ferrara, Leslie A. Naranjo, Sandeep Kumar, Tiziano Gaiotto, Basil Swanson, Andrew R. M. Bradbury
Bioscience Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
Harshini Mukundan
Chemistry Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Corresponding Author

Email: amb@lanl.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FF AB. Performed the experiments: FF LN TG SK. Analyzed the data: FF HM BS AB. Contributed reagents/materials/analysis tools: FF SK HM BS. Wrote the paper: FF AB.