About the Authors

Pascale Rialland

Affiliation Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Simon Authier

Affiliations Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada, CiToxLAB North America, Laval, Quebec, Canada

Martin Guillot

Affiliation Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Jérôme R. E. del Castillo

Affiliation Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Daphnée Veilleux-Lemieux

Affiliation Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Diane Frank

Affiliation Department of Clinical Sciences; Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Dominique Gauvin

Affiliation Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Eric Troncy

eric.troncy@umontreal.ca

Affiliation Groupe de Recherche en Pharmacologie Animale du Québec (GREPAQ), Department of Biomedical Sciences, Faculty of veterinary medicine, Université de Montréal, Saint-Hyacinthe, Quebec, Canada

Competing Interests

The authors received funding for this work from a commercial source (Vétoquinol Laboratories) and with regards to their agreement with this company, this does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. Moreover, the authors contracted the realization of the experiments in a Contract Research Organization, named CiToxLAB North America, and one author, Simon Authier at the time a Ph.D. student under supervision and actually Head of Veterinary Services at this company, participated actively in the study’s realization as well as edition of the manuscript. For this reason, this does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: PR SA DF ET. Performed the experiments: SA DVL ET. Analyzed the data: PR MG JdC DF ET. Contributed reagents/materials/analysis tools: PR SA DG ET. Wrote the paper: PR SA DVL DF ET. Contributed to statistical analysis: MG JdC DG. Critical review of the manuscript: MG JdC DG.