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Research Article

Loss of Imprinting and Allelic Switching at the DLK1-MEG3 Locus in Human Hepatocellular Carcinoma

  • Sumadi Lukman Anwar,

    Affiliation: Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Till Krech,

    Affiliation: Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Britta Hasemeier,

    Affiliation: Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Elisa Schipper,

    Affiliation: Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Nora Schweitzer,

    Affiliation: Department of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Arndt Vogel,

    Affiliation: Department of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Hans Kreipe,

    Affiliation: Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Ulrich Lehmann mail

    Lehmann.Ulrich@MH-Hannover.de

    Affiliation: Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pone.0049462

About the Authors

Sumadi Lukman Anwar, Till Krech, Britta Hasemeier, Elisa Schipper, Hans Kreipe, Ulrich Lehmann
Institute of Pathology, Medizinische Hochschule Hannover, Hannover, Germany
Nora Schweitzer, Arndt Vogel
Department of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule Hannover, Hannover, Germany

Corresponding Author

Email: Lehmann.Ulrich@MH-Hannover.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SLA HK UL. Performed the experiments: SLA BH ES. Analyzed the data: SLA AV HK UL. Contributed reagents/materials/analysis tools: TK NS AV HK. Wrote the paper: SLA UL.