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Research Article

Alcohol Reward Is Increased after Roux-en-Y Gastric Bypass in Dietary Obese Rats with Differential Effects following Ghrelin Antagonism

  • Andras Hajnal mail,

    ahajnal@psu.edu

    Affiliations: Department of Neural and Behavioral Sciences, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America, Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Alevtina Zharikov,

    Affiliation: Department of Neural and Behavioral Sciences, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • James E. Polston,

    Affiliation: Department of Neural and Behavioral Sciences, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Maxine R. Fields,

    Affiliation: Department of Neural and Behavioral Sciences, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Jonathan Tomasko,

    Affiliation: Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Ann M. Rogers,

    Affiliation: Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

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  • Nora D. Volkow,

    Affiliation: Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism Intramural Program, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Panayotis K. Thanos

    Affiliations: Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism Intramural Program, National Institutes of Health, Bethesda, Maryland, United States of America, Behavioral Neuropharmacology and Neuroimaging Lab, Brookhaven National Laboratory, Upton, New York, United States of America

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  • Published: November 07, 2012
  • DOI: 10.1371/journal.pone.0049121

About the Authors

Andras Hajnal, Alevtina Zharikov, James E. Polston, Maxine R. Fields
Department of Neural and Behavioral Sciences, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
Andras Hajnal, Jonathan Tomasko, Ann M. Rogers
Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
Nora D. Volkow, Panayotis K. Thanos
Laboratory of Neuroimaging, National Institute on Alcohol Abuse and Alcoholism Intramural Program, National Institutes of Health, Bethesda, Maryland, United States of America
Panayotis K. Thanos
Behavioral Neuropharmacology and Neuroimaging Lab, Brookhaven National Laboratory, Upton, New York, United States of America

Corresponding Author

Email: ahajnal@psu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AH NDV PKT. Performed the experiments: AZ MRF JT AMR. Analyzed the data: AH AZ JEP MRF. Wrote the paper: AH JEP NDV PKT.