Advertisement
Research Article

Effects of Slow Deep Breathing at High Altitude on Oxygen Saturation, Pulmonary and Systemic Hemodynamics

  • Grzegorz Bilo,

    Affiliation: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

    X
  • Miriam Revera,

    Affiliation: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

    X
  • Maurizio Bussotti,

    Affiliation: Cardiologia Riabilitativa, Fondazione Salvatore Maugeri, IRCCS, Milan, Italy

    X
  • Daniele Bonacina,

    Affiliation: Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

    X
  • Katarzyna Styczkiewicz,

    Affiliation: I Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland

    X
  • Gianluca Caldara,

    Affiliation: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

    X
  • Alessia Giglio,

    Affiliation: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

    X
  • Andrea Faini,

    Affiliation: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

    X
  • Andrea Giuliano,

    Affiliations: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

    X
  • Carolina Lombardi,

    Affiliation: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy

    X
  • Kalina Kawecka-Jaszcz,

    Affiliation: I Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland

    X
  • Giuseppe Mancia,

    Affiliation: Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

    X
  • Piergiuseppe Agostoni mail,

    piergiuseppe.agostoni@unimi.it

    Affiliation: Centro Cardiologico Monzino, IRCCS, and Department of Cardiovascular Sciences, University of Milan, Milan, Italy

    X
  • Gianfranco Parati

    Affiliations: Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy

    X
  • Published: November 12, 2012
  • DOI: 10.1371/journal.pone.0049074

About the Authors

Grzegorz Bilo, Miriam Revera, Gianluca Caldara, Alessia Giglio, Andrea Faini, Andrea Giuliano, Carolina Lombardi, Gianfranco Parati
Department of Cardiology, San Luca Hospital, Istituto Auxologico Italiano, Milan, Italy
Maurizio Bussotti
Cardiologia Riabilitativa, Fondazione Salvatore Maugeri, IRCCS, Milan, Italy
Daniele Bonacina, Andrea Giuliano, Giuseppe Mancia, Gianfranco Parati
Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Milan, Italy
Katarzyna Styczkiewicz, Kalina Kawecka-Jaszcz
I Department of Cardiology and Hypertension, Jagiellonian University Medical College, Krakow, Poland
Piergiuseppe Agostoni
Centro Cardiologico Monzino, IRCCS, and Department of Cardiovascular Sciences, University of Milan, Milan, Italy

Corresponding Author

Email: piergiuseppe.agostoni@unimi.it

Competing Interests

The authors have the following interests. Study B was supported with an unrestricted grant from Boehringer-Ingelheim Germany and Banca Intesa San Paolo, Milan, Italy. Sapio Life Italy s.r.l., GE Healthcare, and Intercure Ltd. supplied the devices necessary for this study free of charge. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: PA GB GP GM. Performed the experiments: MR MB DB KS GC AG AF AG CL KK. Analyzed the data: PA GB MR GC. Wrote the paper: PA GP BG.