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Research Article

Diffusion Tensor Metrics as Biomarkers in Alzheimer's Disease

  • Julio Acosta-Cabronero mail,

    jac@cantab.net

    Affiliation: Cognition, Memory and Language Group, Neurology Unit, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Stephanie Alley,

    Affiliation: Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom

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  • Guy B. Williams,

    Affiliation: Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kingdom

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  • George Pengas,

    Affiliation: Cognition, Memory and Language Group, Neurology Unit, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom

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  • Peter J. Nestor

    Affiliations: Cognition, Memory and Language Group, Neurology Unit, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom, German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany

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  • Published: November 07, 2012
  • DOI: 10.1371/journal.pone.0049072

About the Authors

Julio Acosta-Cabronero, George Pengas, Peter J. Nestor
Cognition, Memory and Language Group, Neurology Unit, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom
Stephanie Alley
Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, United Kingdom
Guy B. Williams
Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kingdom
Peter J. Nestor
German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany

Corresponding Author

Email: jac@cantab.net

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JAC GBW PJN. Performed the experiments: JAC GP. Analyzed the data: JAC SA. Wrote the paper: JAC GBW GP PJN.