Advertisement
Research Article

Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid

  • Rakel Brendsdal Forthun,

    Affiliation: Institute of Medicine, Hematology Section, University of Bergen, Bergen, Norway

    X
  • Tanima SenGupta,

    Affiliation: The Biotechnology Centre, University of Oslo, Oslo, Norway

    X
  • Hanne Kim Skjeldam,

    Affiliation: The Biotechnology Centre, University of Oslo, Oslo, Norway

    X
  • Jessica Margareta Lindvall,

    Affiliation: The Biotechnology Centre, University of Oslo, Oslo, Norway

    Current address: Huddinge Genomics Core Facilities, Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

    X
  • Emmet McCormack,

    Affiliations: Institute of Medicine, Hematology Section, University of Bergen, Bergen, Norway, Hematology Section, Department of Medicine, Haukeland University Hospital, Bergen, Norway

    X
  • Bjørn Tore Gjertsen mail,

    bjorn.gjertsen@med.uib.no (BTG); hilde.nilsen@biotek.uio.no (HN)

    Affiliations: Institute of Medicine, Hematology Section, University of Bergen, Bergen, Norway, Hematology Section, Department of Medicine, Haukeland University Hospital, Bergen, Norway

    X
  • Hilde Nilsen mail

    bjorn.gjertsen@med.uib.no (BTG); hilde.nilsen@biotek.uio.no (HN)

    Affiliation: The Biotechnology Centre, University of Oslo, Oslo, Norway

    X
  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0048992

About the Authors

Rakel Brendsdal Forthun, Emmet McCormack, Bjørn Tore Gjertsen
Institute of Medicine, Hematology Section, University of Bergen, Bergen, Norway
Tanima SenGupta, Hanne Kim Skjeldam, Jessica Margareta Lindvall, Hilde Nilsen
The Biotechnology Centre, University of Oslo, Oslo, Norway
Emmet McCormack, Bjørn Tore Gjertsen
Hematology Section, Department of Medicine, Haukeland University Hospital, Bergen, Norway

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BTG HN EM. Performed the experiments: RBF TS HKS EM. Analyzed the data: RBF TS JML HN. Contributed reagents/materials/analysis tools: JML. Wrote the paper: RBF BTG HN.