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Research Article

Inflamm-Aging and Arachadonic Acid Metabolite Differences with Stage of Tendon Disease

  • Stephanie Georgina Dakin mail,

    sdakin@rvc.ac.uk

    Affiliation: Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom

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  • Jayesh Dudhia,

    Affiliation: Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom

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  • Natalie Jayne Werling,

    Affiliation: Department of Biotherapeutics, National Institute for Biological Standards and Control, South Mimms, United Kingdom

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  • Dirk Werling,

    Affiliation: Department of Pathology and Infectious Diseases, Royal Veterinary College, University of London, Hatfield, United Kingdom

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  • Dilkush Robert Ephrem Abayasekara,

    Affiliation: Department of Veterinary Basic Sciences, Royal Veterinary College, University of London, London, United Kingdom

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  • Roger Kenneth Whealands Smith

    Affiliation: Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0048978

About the Authors

Stephanie Georgina Dakin, Jayesh Dudhia, Roger Kenneth Whealands Smith
Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, Hatfield, United Kingdom
Natalie Jayne Werling
Department of Biotherapeutics, National Institute for Biological Standards and Control, South Mimms, United Kingdom
Dirk Werling
Department of Pathology and Infectious Diseases, Royal Veterinary College, University of London, Hatfield, United Kingdom
Dilkush Robert Ephrem Abayasekara
Department of Veterinary Basic Sciences, Royal Veterinary College, University of London, London, United Kingdom

Corresponding Author

Email: sdakin@rvc.ac.uk

Competing Interests

The authors declare the study was in part funded by Ceva (France). There are no other relevant declarations relating to employment, consultancy, patents, products in development or marketed products. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SGD JD DREA RKWS. Performed the experiments: SGD. Analyzed the data: SGD JD NJW RKWS. Contributed reagents/materials/analysis tools: SGD JD RKWS. Wrote the paper: SGD JD NJW DW DREA RKWS.