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Research Article

Segmentation and Visual Analysis of Whole-Body Mouse Skeleton microSPECT

  • Artem Khmelinskii,

    Affiliation: Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Harald C. Groen,

    Affiliation: Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands

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  • Martin Baiker,

    Affiliation: Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

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  • Marion de Jong,

    Affiliations: Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands

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  • Boudewijn P. F. Lelieveldt mail

    b.p.f.lelieveldt@lumc.nl

    Affiliations: Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands, Department of Intelligent Systems, Delft University of Technology, Delft, The Netherlands

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  • Published: November 12, 2012
  • DOI: 10.1371/journal.pone.0048976

About the Authors

Artem Khmelinskii, Martin Baiker, Boudewijn P. F. Lelieveldt
Division of Image Processing, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
Harald C. Groen, Marion de Jong
Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands
Marion de Jong
Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
Boudewijn P. F. Lelieveldt
Department of Intelligent Systems, Delft University of Technology, Delft, The Netherlands

Corresponding Author

Email: b.p.f.lelieveldt@lumc.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AK MB MDJ BPFL. Performed the experiments: AK MB HCG. Analyzed the data: AK MB HCG. Contributed reagents/materials/analysis tools: AK MB HCG. Wrote the paper: AK. Performed the experiments with animals and acquired the data: HCG. Developed the registration/segmentation tool: AK MB. Discussed the results and commented on the manuscript: AK MB HCG MDJ BPFL.