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Research Article

Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

  • Baruch E. Bulvik,

    Affiliation: Departments of Cellular Biochemistry and Human Genetics, Faculties of Dental Medicine and Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

    This paper is part of the Ph.D. thesis of BEB approved by the Hebrew University of Jerusalem, May 2012.

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  • Eduard Berenshtein,

    Affiliation: Departments of Cellular Biochemistry and Human Genetics, Faculties of Dental Medicine and Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Esther G. Meyron-Holtz,

    Affiliation: Laboratory for Molecular Nutrition, Faculty of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Technion City, Haifa, Israel

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  • Abraham M. Konijn equal contributor mail,

    equal contributor Contributed equally to this work with: Abraham M. Konijn, Mordechai Chevion

    amkonijn@gmail.com

    Affiliation: Human Nutrition and Metabolism, Faculties of Dental Medicine and Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Mordechai Chevion equal contributor

    equal contributor Contributed equally to this work with: Abraham M. Konijn, Mordechai Chevion

    Affiliation: Departments of Cellular Biochemistry and Human Genetics, Faculties of Dental Medicine and Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Published: November 14, 2012
  • DOI: 10.1371/journal.pone.0048947

About the Authors

Baruch E. Bulvik, Eduard Berenshtein, Mordechai Chevion
Departments of Cellular Biochemistry and Human Genetics, Faculties of Dental Medicine and Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
Abraham M. Konijn
Human Nutrition and Metabolism, Faculties of Dental Medicine and Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
Esther G. Meyron-Holtz
Laboratory for Molecular Nutrition, Faculty of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Technion City, Haifa, Israel

Corresponding Author

Email: amkonijn@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BEB MC AMK. Performed the experiments: BEB EB EGMH. Analyzed the data: BEB EB MC AMK. Contributed reagents/materials/analysis tools: AMK EGMH. Wrote the paper: BEB AMK MC.