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Research Article

Modeling the Role of Negative Cooperativity in Metabolic Regulation and Homeostasis

  • Eliot C. Bush mail,

    eliot.bush@hmc.edu

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Anne E. Clark,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Chris M. DeBoever,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Lillian E. Haynes,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Sidra Hussain,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Singer Ma,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Matthew M. McDermott,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Adam M. Novak,

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • John S. Wentworth

    Affiliation: Department of Biology, Harvey Mudd College, Claremont, California, United States of America

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  • Published: November 09, 2012
  • DOI: 10.1371/journal.pone.0048920

About the Authors

Eliot C. Bush, Anne E. Clark, Chris M. DeBoever, Lillian E. Haynes, Sidra Hussain, Singer Ma, Matthew M. McDermott, Adam M. Novak, John S. Wentworth
Department of Biology, Harvey Mudd College, Claremont, California, United States of America

Corresponding Author

Email: eliot.bush@hmc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EB. Performed the experiments: EB AC CD LH SH SM MM AN JW. Analyzed the data: EB SH. Wrote the paper: EB.