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Research Article

Self-Renewal and Pluripotency Acquired through Somatic Reprogramming to Human Cancer Stem Cells

  • Shogo Nagata,

    Affiliation: Department of Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

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  • Kunio Hirano,

    Affiliation: Department of Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

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  • Michele Kanemori,

    Affiliation: Department of Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

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  • Liang-Tso Sun,

    Affiliation: Department of Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

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  • Takashi Tada mail

    ttada@frontier.kyoto-u.ac.jp

    Affiliation: Department of Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pone.0048699

About the Authors

Shogo Nagata, Kunio Hirano, Michele Kanemori, Liang-Tso Sun, Takashi Tada
Department of Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

Corresponding Author

Email: ttada@frontier.kyoto-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TT. Performed the experiments: SN KH MK LTS TT. Analyzed the data: SN KH MK LTS TT. Wrote the paper: SN TT.