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Research Article

The HIV-1 Rev Protein Enhances Encapsidation of Unspliced and Spliced, RRE-Containing Lentiviral Vector RNA

  • Bastian Grewe mail,

    Bastian.Grewe@rub.de

    Affiliation: Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

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  • Katrin Ehrhardt,

    Affiliation: Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

    Current address: Institute of Virology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany

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  • Bianca Hoffmann,

    Affiliation: Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

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  • Maik Blissenbach,

    Affiliation: Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

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  • Sabine Brandt,

    Affiliation: Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

    Current address: Serology/Immunology, Medical Laboratory of Bremen, Bremen, Germany

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  • Klaus Überla

    Affiliation: Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

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  • Published: November 01, 2012
  • DOI: 10.1371/journal.pone.0048688

About the Authors

Bastian Grewe, Katrin Ehrhardt, Bianca Hoffmann, Maik Blissenbach, Sabine Brandt, Klaus Überla
Department of Molecular and Medical Virology, Ruhr-University Bochum, Bochum, Germany

Corresponding Author

Email: Bastian.Grewe@rub.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BG SB KÜ. Performed the experiments: BG KE MB SB. Analyzed the data: BG SB KÜ. Contributed reagents/materials/analysis tools: MB BH. Wrote the paper: BG BH KÜ.