# wombat urls ß PLOS ONE: Impact of Xpert MTB/RIF Testing on Tuberculosis Management and Outcomes in Hospitalized Patients in Uganda
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Research Article

Impact of Xpert MTB/RIF Testing on Tuberculosis Management and Outcomes in Hospitalized Patients in Uganda

  • Christina Yoon equal contributor,

    equal contributor Contributed equally to this work with: Christina Yoon, Adithya Cattamanchi

    Affiliation: Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

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  • Adithya Cattamanchi equal contributor mail,

    equal contributor Contributed equally to this work with: Christina Yoon, Adithya Cattamanchi

    acattamanchi@medsfgh.ucsf.edu

    Affiliations: Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America, Curry International Tuberculosis Center, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

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  • J. Lucian Davis,

    Affiliations: Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America, Curry International Tuberculosis Center, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

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  • William Worodria,

    Affiliations: Department of Medicine, Faculty of Medicine, Makerere University, Kampala, Uganda, Uganda Ministry of Health, Kampala, Uganda

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  • Saskia den Boon,

    Affiliation: Makerere University-University of California San Francisco Research Collaboration, Kampala, Uganda

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  • Nelson Kalema,

    Affiliation: Makerere University-University of California San Francisco Research Collaboration, Kampala, Uganda

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  • Winceslaus Katagira,

    Affiliation: Makerere University-University of California San Francisco Research Collaboration, Kampala, Uganda

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  • Sylvia Kaswabuli,

    Affiliation: Makerere University-University of California San Francisco Research Collaboration, Kampala, Uganda

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  • Cecily Miller,

    Affiliation: Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

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  • Alfred Andama,

    Affiliation: Department of Medicine, Faculty of Medicine, Makerere University, Kampala, Uganda

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  • Heidi Albert,

    Affiliation: Foundation for Innovative New Diagnostics, Kampala, Uganda

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  • Pamela Nabeta,

    Affiliation: Foundation for Innovative New Diagnostics, Geneva, Switzerland

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  • Christen Gray,

    Affiliation: Foundation for Innovative New Diagnostics, Geneva, Switzerland

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  • Irene Ayakaka,

    Affiliation: Makerere University-University of California San Francisco Research Collaboration, Kampala, Uganda

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  • Laurence Huang

    Affiliations: Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America, HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America

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  • Published: November 06, 2012
  • DOI: 10.1371/journal.pone.0048599

About the Authors

Christina Yoon, Adithya Cattamanchi, J. Lucian Davis, Cecily Miller, Laurence Huang
Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
Adithya Cattamanchi, J. Lucian Davis
Curry International Tuberculosis Center, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
Laurence Huang
HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America
William Worodria, Alfred Andama
Department of Medicine, Faculty of Medicine, Makerere University, Kampala, Uganda
William Worodria
Uganda Ministry of Health, Kampala, Uganda
Saskia den Boon, Nelson Kalema, Winceslaus Katagira, Sylvia Kaswabuli, Irene Ayakaka
Makerere University-University of California San Francisco Research Collaboration, Kampala, Uganda
Heidi Albert
Foundation for Innovative New Diagnostics, Kampala, Uganda
Pamela Nabeta, Christen Gray
Foundation for Innovative New Diagnostics, Geneva, Switzerland

Corresponding Author

Email: acattamanchi@medsfgh.ucsf.edu

Competing Interests

The authors have read the journal’s policy and have the following conflicts: 1) AC is an Academic Editor of PLOS ONE. 2) HA, PN and CG work for the Foundation for Innovative New Diagnostics (FIND), a nonprofit organization whose mission is to drive the development and early implementation of diagnostic tests that have a high impact on patient care in low and middle-resource settings. FIND partnered with Cepheid in the development and initial evaluation of the Xpert MTB/RIF assay. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AC JLD. Performed the experiments: WW SdB NK WK SK IA. Analyzed the data: CY AC JLD CM. Wrote the paper: CY AC. Critically reviewed the manuscript: LH JLD PN SdB WW HA CG. Approved the final manuscript: CY AC JLD WW SdB NK WK SK CM AA HA PN CG IA LH.