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Research Article

HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

  • Sandeep N. Shah,

    Affiliations: Hematology Division, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Candace Kerr,

    Affiliation: Obstetrics & Gynecology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Leslie Cope,

    Affiliations: Oncology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Biostatistics, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Elias Zambidis,

    Affiliations: Oncology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Comparative Molecular & Pathobiology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Cyndi Liu,

    Affiliation: Obstetrics & Gynecology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Joelle Hillion,

    Affiliation: Hematology Division, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Amy Belton,

    Affiliations: Hematology Division, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • David L. Huso,

    Affiliations: Oncology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Comparative Molecular & Pathobiology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Pathology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Linda M. S. Resar mail

    lresar@jhmi.edu

    Affiliations: Hematology Division, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Oncology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Pediatrics, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Published: November 15, 2012
  • DOI: 10.1371/journal.pone.0048533

About the Authors

Sandeep N. Shah, Joelle Hillion, Amy Belton, Linda M. S. Resar
Hematology Division, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Sandeep N. Shah, Amy Belton, Linda M. S. Resar
Department of Medicine, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Candace Kerr, Cyndi Liu
Obstetrics & Gynecology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Leslie Cope, Elias Zambidis, David L. Huso, Linda M. S. Resar
Oncology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Leslie Cope
Biostatistics, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Elias Zambidis, David L. Huso
Comparative Molecular & Pathobiology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
David L. Huso
Pathology, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Linda M. S. Resar
Pediatrics, the Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Corresponding Author

Email: lresar@jhmi.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SNS CK LC EZ DLH LMSR. Performed the experiments: SNS CK LC EZ CL JH AB DLH. Analyzed the data: SNS CK LC EZ CL JH DLH LMSR. Wrote the paper: SNS LMSR.