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Research Article

Tubulointerstitial De Novo Expression of the α8 Integrin Chain in a Rodent Model of Renal Fibrosis – A Potential Target for Anti-Fibrotic Therapy?

  • Andrea Hartner equal contributor mail,

    equal contributor Contributed equally to this work with: Andrea Hartner, Carlos Menendez-Castro

    andrea.hartner@uk-erlangen.de

    Affiliation: Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany

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  • Carlos Menendez-Castro equal contributor,

    equal contributor Contributed equally to this work with: Andrea Hartner, Carlos Menendez-Castro

    Affiliation: Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany

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  • Nada Cordasic,

    Affiliation: Department of Nephrology and Hypertension, University Hospital of Erlangen, Erlangen, Germany

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  • Ines Marek,

    Affiliation: Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany

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  • Gudrun Volkert,

    Affiliation: Department of Nephrology and Hypertension, University Hospital of Erlangen, Erlangen, Germany

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  • Bernd Klanke,

    Affiliation: Department of Nephrology and Hypertension, University Hospital of Erlangen, Erlangen, Germany

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  • Wolfgang Rascher,

    Affiliation: Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany

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  • Karl F. Hilgers

    Affiliation: Department of Nephrology and Hypertension, University Hospital of Erlangen, Erlangen, Germany

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pone.0048362

About the Authors

Andrea Hartner, Carlos Menendez-Castro, Ines Marek, Wolfgang Rascher
Department of Pediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany
Nada Cordasic, Gudrun Volkert, Bernd Klanke, Karl F. Hilgers
Department of Nephrology and Hypertension, University Hospital of Erlangen, Erlangen, Germany

Corresponding Author

Email: andrea.hartner@uk-erlangen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AH CMC KFH WR. Performed the experiments: IM GV NC BK. Analyzed the data: AH IM NC BK. Wrote the paper: AH CMC KFH.