About the Authors
- Clare M. Lee
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Affiliation Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom
- Manikhandan A. V. Mudaliar
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Affiliation College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
- D. R. Haggart
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Affiliation Epsistem Ltd., Manchester, United Kingdom
- C. Roland Wolf
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Affiliations University of Dundee Medical Research Institute, Ninewells Hospital & Medical School, Dundee, United Kingdom, CXR Biosciences Ltd, Dundee, United Kingdom
- Gino Miele
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Affiliation Epsistem Ltd., Manchester, United Kingdom
- J. Keith Vass
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Affiliation Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom
- Desmond J. Higham
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* E-mail: d.j.higham@strath.ac.uk
Affiliation Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom
- Daniel Crowther
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Affiliation Sanofi, Frankfurt am Main, Germany
Competing Interests
DC was employed by Pfizer and legacy company Wyeth during the course of this work and is now employed by Sanofi. GM was employed by Pfizer and legacy company Wyeth during the course of this work and is now employed by Epistem. CRW is employed by CXR. Pfizer agreed to the publication of this manuscript. MM, DRH and JKV were funded through the TMRC. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CML MAVM DRH CRW GM JKV DJH DC. Performed the experiments: CML MAVM DRH CRW GM JKV DJH DC. Analyzed the data: CML MAVM JKV DJH DC. Contributed reagents/materials/analysis tools: CML MAVM DRH CRW GM JKV DJH DC. Wrote the paper: CML MAVM JKV DJH DC.