About the Authors

Vincent A. Emanuele II

VEmanueleII@cdc.gov

Affiliation Chronic and Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Gitika Panicker

Affiliation Chronic and Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Brian M. Gurbaxani

Affiliation Chronic and Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Jin-Mann S. Lin

Affiliation Chronic and Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Elizabeth R. Unger

Affiliation Chronic and Viral Diseases Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America

Competing Interests

Authors VAE and BMG have a pending patent application entitled, “Use of detector response curves to optimize settings for mass spectrometry,” application number PCT/US2011/055376 and depending from U.S. Provisional Application No. 61/390,910. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Wrote the paper: VAE GP BMG. Conceived and designed computational experiments, performed computational experiments, analyzed the data with LibSELDI and manually validated peaks: VAE. Conceived and designed laboratory experiments: GP ERU. Performed laboratory experiments, analyzed the data with Ciphergen Express and manually validated peaks: GP. Provided biological interpretation of the data: BMG. Provided statistical interpretation of the clinical data: J-MSL. Revised manuscript critically for important intellectual content: J-MSL ERU.