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Research Article

The Limits of De Novo DNA Motif Discovery

  • David Simcha mail,

    dsimcha1@jhmi.edu

    Affiliation: Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Nathan D. Price,

    Affiliation: Institute for Systems Biology, Seattle, Washington, United States of America

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  • Donald Geman

    Affiliation: Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Published: November 07, 2012
  • DOI: 10.1371/journal.pone.0047836

About the Authors

David Simcha
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America
Nathan D. Price
Institute for Systems Biology, Seattle, Washington, United States of America
Donald Geman
Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, Maryland, United States of America

Corresponding Author

Email: dsimcha1@jhmi.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DS NP DG. Performed the experiments: DS. Analyzed the data: DS NP DG. Wrote the paper: DS NP DG.