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Research Article

Soluble IL-2Rα (sCD25) Exacerbates Autoimmunity and Enhances the Development of Th17 Responses in Mice

  • Shane E. Russell,

    Affiliations: Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland, National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland

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  • Anne C. Moore,

    Affiliation: School of Pharmacy, University College Cork, Cork, Ireland

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  • Padraic G. Fallon,

    Affiliations: Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland, National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland

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  • Patrick T. Walsh mail

    walshp10@tcd.ie

    Affiliations: Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland, National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland

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  • Published: October 15, 2012
  • DOI: 10.1371/journal.pone.0047748

About the Authors

Shane E. Russell, Padraic G. Fallon, Patrick T. Walsh
Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland
Shane E. Russell, Padraic G. Fallon, Patrick T. Walsh
National Children's Research Centre, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland
Anne C. Moore
School of Pharmacy, University College Cork, Cork, Ireland

Corresponding Author

Email: walshp10@tcd.ie

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PTW. Performed the experiments: SER. Analyzed the data: SER ACM PGF PTW. Contributed reagents/materials/analysis tools: PGF. Wrote the paper: SER PTW.