About the Authors

Dominic Holland

dominic.holland@gmail.com

Affiliation Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

Linda K. McEvoy

Affiliation Department of Radiology, University of California San Diego, La Jolla, California, United States of America

Rahul S. Desikan

Affiliation Department of Radiology, University of California San Diego, La Jolla, California, United States of America

Anders M. Dale

Affiliations Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America, Department of Radiology, University of California San Diego, La Jolla, California, United States of America

for the Alzheimer’s Disease Neuroimaging Initiative

Membership of the Alzheimer’s Disease Neuroimaging Initiative is provided in the Acknowledgments.

Competing Interests

Anders M. Dale is a founder and holds equity in CorTechs Labs, Inc, and also serves on its Scientific Advisory Board. The terms of this arrangement have been reviewed and approved by the University of California San Diego in accordance with its conflict of interest policies. Linda K. McEvoy’s spouse is President of CorTechs Labs, Inc. A patent application for Quarc has been filed through the UCSD Technology Transfer Office.

Author Contributions

Conceived and designed the experiments: DH. Performed the experiments: DH. Analyzed the data: DH AMD. Contributed reagents/materials/analysis tools: DH AMD. Wrote the paper: DH LKM RSD. Responsible for the study concept and design, all levels of data analysis, drafting the report, tables, and figures: DH. Contributed critically to data interpretation and revision of the report: DH LKM RSD. Contributed to data acquisition and analysis: AMD.