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Research Article

Characterizing the Mechanism of Action of Double-Stranded RNA Activity against Western Corn Rootworm (Diabrotica virgifera virgifera LeConte)

  • Renata Bolognesi,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Parthasarathy Ramaseshadri mail,

    pprama1@monsanto.com

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Jerry Anderson,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Pamela Bachman,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • William Clinton,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Ronald Flannagan,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Oliver Ilagan,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Christina Lawrence,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • Steven Levine,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • William Moar,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • Geoffrey Mueller,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • Jianguo Tan,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • Joshua Uffman,

    Affiliation: Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

    X
  • Elizabeth Wiggins,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Gregory Heck,

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

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  • Gerrit Segers

    Affiliation: Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America

    X
  • Published: October 11, 2012
  • DOI: 10.1371/journal.pone.0047534

About the Authors

Renata Bolognesi, Parthasarathy Ramaseshadri, Jerry Anderson, William Clinton, Ronald Flannagan, Oliver Ilagan, Elizabeth Wiggins, Gregory Heck, Gerrit Segers
Biotechnology Division, Monsanto Company, Chesterfield, Missouri, United States of America
Pamela Bachman, Christina Lawrence, Steven Levine, William Moar, Geoffrey Mueller, Jianguo Tan, Joshua Uffman
Regulatory Division, Monsanto Company, St. Louis, Missouri, United States of America

Corresponding Author

Email: pprama1@monsanto.com

Competing Interests

All authors are affiliated to Monsanto Company, USA. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RB GS PR SL GH CL. Performed the experiments: JA PB EW. Analyzed the data: RB PR PB RF CL WM. Contributed reagents/materials/analysis tools: WC OI GM JT JU. Wrote the paper: RB.