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Research Article

A Cost Effectiveness and Capacity Analysis for the Introduction of Universal Rotavirus Vaccination in Kenya: Comparison between Rotarix and RotaTeq Vaccines

  • Albert Jan van Hoek,

    Affiliation: Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency, London, United Kingdom

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  • Mwanajuma Ngama mail,

    MNgama@kemri-wellcome.org

    Affiliation: Kenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya

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  • Amina Ismail,

    Affiliation: Division of Disease Surveillance and Response, Ministry of Public Health and Sanitation, Nairobi, Kenya

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  • Jane Chuma,

    Affiliation: Kenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya

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  • Samuel Cheburet,

    Affiliation: Health Information System, Ministry of Health, Nairobi, Kenya

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  • David Mutonga,

    Affiliation: Division of Disease Surveillance and Response, Ministry of Public Health and Sanitation, Nairobi, Kenya

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  • Tatu Kamau,

    Affiliation: Division of Vaccines & Immunization, Ministry of Public Health and Sanitation, Nairobi, Kenya

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  • D. James Nokes

    Affiliations: Kenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya, School of Life Sciences, University of Warwick, Coventry, United Kingdom

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  • Published: October 24, 2012
  • DOI: 10.1371/journal.pone.0047511

About the Authors

Albert Jan van Hoek
Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency, London, United Kingdom
Mwanajuma Ngama, Jane Chuma, D. James Nokes
Kenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya
Amina Ismail, David Mutonga
Division of Disease Surveillance and Response, Ministry of Public Health and Sanitation, Nairobi, Kenya
Samuel Cheburet
Health Information System, Ministry of Health, Nairobi, Kenya
Tatu Kamau
Division of Vaccines & Immunization, Ministry of Public Health and Sanitation, Nairobi, Kenya
D. James Nokes
School of Life Sciences, University of Warwick, Coventry, United Kingdom

Corresponding Author

Email: MNgama@kemri-wellcome.org

Competing Interests

The authors have read the journal’s policy and have the following conflicts: JN has received travel and accommodation support to attend a meeting (2/12/11) convened by GSK at which he acted as a scientific advisor. TK is head of the Division of Vaccines and Immunization, MoPHS Kenya and identified to GAVI the preference to use the GSK Rotarix vaccine for Kenya. This decision was made after the current project was conceived but before its completion. The decision had no influence over the analysis or interpretation of the results presented in this paper. This does not alter the authors’ adherence to all PLoS policies on sharing data and material.

Author Contributions

Conceived and designed the experiments: AJvH JN. Performed the experiments: AJvH MN AI TK SC DM. Analyzed the data: AJvH. Contributed reagents/materials/analysis tools: AJvH AI MN JC SC TK DM JN. Wrote the paper: AJvH.