About the Authors

Jared A. Niska

Affiliation Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

Jeffrey A. Meganck

Affiliation Caliper – a PerkinElmer Company, Alameda, California, United States of America

Jonathan R. Pribaz

Affiliation Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

Jonathan H. Shahbazian

Affiliation Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Ed Lim

Affiliation Caliper – a PerkinElmer Company, Alameda, California, United States of America

Ning Zhang

Affiliation Caliper – a PerkinElmer Company, Alameda, California, United States of America

Brad W. Rice

Affiliation Caliper – a PerkinElmer Company, Alameda, California, United States of America

Ali Akin

Affiliations Caliper – a PerkinElmer Company, Alameda, California, United States of America, Novartis Institutes for BioMedical Research, Inc., Emeryville, California, United States of America

Romela Irene Ramos

Affiliation Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Nicholas M. Bernthal

Affiliation Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

Kevin P. Francis

Affiliation Caliper – a PerkinElmer Company, Alameda, California, United States of America

Lloyd S. Miller

lloydmiller@jhmi.edu

Affiliation Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors Jeffrey A. Meganck, Ed Lim, Ning Zhang, Brad W. Rice and Kevin P. Francis are paid employees of Caliper - a PerkinElmer Company and Ali Akin is a paid employee of Novartis Institutes for BioMedical Research, Inc. These authors are paid employees of these companies. They do not have any ownership of stock, consultancy, patents, products in development or marketed products and they do not have any other competing interests other than the paid employment. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JAN JAM JRP NZ BWR NMB KPF LSM. Performed the experiments: JAN JAM JRP JHS EL NZ AA RIR. Analyzed the data: JAN JAM JRP JHS EL AA. Contributed reagents/materials/analysis tools: JAM ED NZ BWR KPF. Wrote the paper: JAN JAM JRP NMB KPF LSM.