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Research Article

Simple Monitoring of Gene Targeting Efficiency in Human Somatic Cell Lines Using the PIGA Gene

  • Sivasundaram Karnan,

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Yuko Konishi,

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Akinobu Ota,

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Miyuki Takahashi,

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Lkhagvasuren Damdindorj,

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Yoshitaka Hosokawa,

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Hiroyuki Konishi mail

    hkonishi@aichi-med-u.ac.jp

    Affiliation: Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

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  • Published: October 08, 2012
  • DOI: 10.1371/journal.pone.0047389

About the Authors

Sivasundaram Karnan, Yuko Konishi, Akinobu Ota, Miyuki Takahashi, Lkhagvasuren Damdindorj, Yoshitaka Hosokawa, Hiroyuki Konishi
Department of Biochemistry, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan

Corresponding Author

Email: hkonishi@aichi-med-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SK YK HK. Performed the experiments: SK YK. Analyzed the data: SK YK AO MT LD YH HK. Wrote the paper: SK YK HK.