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Research Article

Lentiviral-Mediated RNAi Knockdown of Cbfa1 Gene Inhibits Endochondral Ossification of Antler Stem Cells in Micromass Culture

  • Hongmei Sun,

    Affiliations: Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, Jilin, P. R. China, State Key Laboratory for Molecular Biology of Special Economic Animals, Jilin, P. R. China

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  • Fuhe Yang,

    Affiliations: Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, Jilin, P. R. China, State Key Laboratory for Molecular Biology of Special Economic Animals, Jilin, P. R. China

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  • Wenhui Chu,

    Affiliations: Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, Jilin, P. R. China, State Key Laboratory for Molecular Biology of Special Economic Animals, Jilin, P. R. China

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  • Haiping Zhao,

    Affiliations: Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, Jilin, P. R. China, State Key Laboratory for Molecular Biology of Special Economic Animals, Jilin, P. R. China

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  • Chris McMahon,

    Affiliation: AgResearch, Invermay Agricultural Centre, Mosgiel, New Zealand

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  • Chunyi Li mail

    chunyi.li@agresearch.co.nz

    Affiliations: AgResearch, Invermay Agricultural Centre, Mosgiel, New Zealand, State Key Laboratory for Molecular Biology of Special Economic Animals, Jilin, P. R. China

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0047367

About the Authors

Hongmei Sun, Fuhe Yang, Wenhui Chu, Haiping Zhao
Institute of Special Wild Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, Jilin, P. R. China
Chris McMahon, Chunyi Li
AgResearch, Invermay Agricultural Centre, Mosgiel, New Zealand
Hongmei Sun, Fuhe Yang, Wenhui Chu, Haiping Zhao, Chunyi Li
State Key Laboratory for Molecular Biology of Special Economic Animals, Jilin, P. R. China

Corresponding Author

Email: chunyi.li@agresearch.co.nz

Competing Interests

Chunyi Li and Chris McMahon are employees of AgResearch New Zealand Ltd; Hongmei Sun, Fuhe Yang, Wenhui Chu and Haiping Zhao are employees of Chinese Academy of Agricultural Sciences. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. These authors receive a salary as employees, but have not benefited from this research in any other way.

Author Contributions

Conceived and designed the experiments: CL HS FY. Performed the experiments: HS WC HZ CL. Analyzed the data: HS CL CM. Wrote the paper: CL HS FY CM.