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Research Article

LBoost: A Boosting Algorithm with Application for Epistasis Discovery

  • Bethany J. Wolf mail,

    wolfb@musc.edu

    Affiliation: Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Elizabeth G. Hill,

    Affiliation: Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Elizabeth H. Slate,

    Affiliation: Department of Statistics, Florida State University, Tallahassee, Florida, United States of America

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  • Carola A. Neumann,

    Affiliation: Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Emily Kistner-Griffin

    Affiliation: Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Published: November 08, 2012
  • DOI: 10.1371/journal.pone.0047281

About the Authors

Bethany J. Wolf, Elizabeth G. Hill, Emily Kistner-Griffin
Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, United States of America
Elizabeth H. Slate
Department of Statistics, Florida State University, Tallahassee, Florida, United States of America
Carola A. Neumann
Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, United States of America

Corresponding Author

Email: wolfb@musc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BW EH ES EK-G. Performed the experiments: BW EK-G. Analyzed the data: BW EK-G. Contributed reagents/materials/analysis tools: BW EK-G. Wrote the paper: BW EH ES CN EK-G. Obtained permission for use of the CGEMS data: EK-G.