Advertisement
Research Article

Selective Decline of Synaptic Protein Levels in the Frontal Cortex of Female Mice Deficient in the Extracellular Metalloproteinase ADAMTS1

  • Matthew D. Howell,

    Affiliation: University of Arkansas for Medical Sciences, Department of Pharmacology and Toxicology, Little Rock, Arkansas, United States of America

    X
  • Antoni X. Torres-Collado,

    Affiliation: University of California, Los Angeles, Department of Molecular, Cell, and Developmental Biology, Los Angeles, California, United States of America

    X
  • M. Luisa Iruela-Arispe,

    Affiliation: University of California, Los Angeles, Department of Molecular, Cell, and Developmental Biology, Los Angeles, California, United States of America

    X
  • Paul E. Gottschall mail

    pegottschall@uams.edu

    Affiliation: University of Arkansas for Medical Sciences, Department of Pharmacology and Toxicology, Little Rock, Arkansas, United States of America

    X
  • Published: October 11, 2012
  • DOI: 10.1371/journal.pone.0047226

About the Authors

Matthew D. Howell, Paul E. Gottschall
University of Arkansas for Medical Sciences, Department of Pharmacology and Toxicology, Little Rock, Arkansas, United States of America
Antoni X. Torres-Collado, M. Luisa Iruela-Arispe
University of California, Los Angeles, Department of Molecular, Cell, and Developmental Biology, Los Angeles, California, United States of America

Corresponding Author

Email: pegottschall@uams.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDH PEG. Performed the experiments: MDH. Analyzed the data: MDH PEG. Contributed reagents/materials/analysis tools: AXTC MLIA PEG. Wrote the paper: MDH PEG. Provided insight and assistance with breeding the ADAMTS null mouse: AXTC MLIA.