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Research Article

Induction of HCA587-Specific Antitumor Immunity with HCA587 Protein Formulated with CpG and ISCOM in Mice

  • Juanjuan Chen equal contributor,

    equal contributor Contributed equally to this work with: Juanjuan Chen, Lijie Zhang

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Lijie Zhang equal contributor,

    equal contributor Contributed equally to this work with: Juanjuan Chen, Lijie Zhang

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Weigang Wen,

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Jiaqing Hao,

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Pumei Zeng,

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Xiaoping Qian,

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Yu Zhang mail,

    zhangyu007@bjmu.edu.cn (YZ); yinyanhui@bjmu.edu.cn (YY)

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

    X
  • Yanhui Yin mail

    zhangyu007@bjmu.edu.cn (YZ); yinyanhui@bjmu.edu.cn (YY)

    Affiliation: Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

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  • Published: October 11, 2012
  • DOI: 10.1371/journal.pone.0047219

About the Authors

Juanjuan Chen, Lijie Zhang, Weigang Wen, Jiaqing Hao, Pumei Zeng, Xiaoping Qian, Yu Zhang, Yanhui Yin
Department of Immunology, School of Basic Medical Sciences, and Key Laboratory of Medical Immunology of Ministry of Health, Peking University Health Science Center, Beijing, People’s Republic of China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JC LZ YY. Performed the experiments: JC LZ WW. Analyzed the data: JC LZ JH YZ YY. Contributed reagents/materials/analysis tools: PZ XQ. Wrote the paper: JC YZ YY.