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Research Article

Identification and Characterization of Two Novel blaKLUC Resistance Genes through Large-Scale Resistance Plasmids Sequencing

  • Teng Xu equal contributor,

    equal contributor Contributed equally to this work with: Teng Xu, Jun Ying

    Affiliations: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China, The Key Laboratory of Mammalian Reproductive Biology and Biotechnology of the Ministry of Education, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, People’s Republic of China

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  • Jun Ying equal contributor,

    equal contributor Contributed equally to this work with: Teng Xu, Jun Ying

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Xiaoding Yao,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Yulong Song,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Ping Ma,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Bokan Bao,

    Affiliation: College of Biological Science, Agricultural University of China, Beijing, People’s Republic of China

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  • Weiyan Jiang,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Xinmei Wu,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Huifen Tou,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Peizhen Li,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Ping Ren,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Jingxian Fei,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Lei Yang,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Qi Liu,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Zuyuan Xu,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Tieli Zhou,

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Liyan Ni mail,

    nily2001@126.com (LN); baoqy@genomics.org.cn (QB)

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Qiyu Bao mail

    nily2001@126.com (LN); baoqy@genomics.org.cn (QB)

    Affiliation: Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0047197

About the Authors

Teng Xu, Jun Ying, Xiaoding Yao, Yulong Song, Ping Ma, Weiyan Jiang, Xinmei Wu, Huifen Tou, Peizhen Li, Ping Ren, Jingxian Fei, Lei Yang, Qi Liu, Zuyuan Xu, Tieli Zhou, Liyan Ni, Qiyu Bao
Institute of Biomedical Informatics/Zhejiang Provincial Key Laboratory of Medical Genetics, Wenzhou Medical College, Wenzhou, Zhejiang, People’s Republic of China
Teng Xu
The Key Laboratory of Mammalian Reproductive Biology and Biotechnology of the Ministry of Education, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, People’s Republic of China
Bokan Bao
College of Biological Science, Agricultural University of China, Beijing, People’s Republic of China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: QB LN TX. Performed the experiments: TX JY XY YS PM BB WJ XW PR JF QL. Analyzed the data: TX JY BB HT PL QL LY. Contributed reagents/materials/analysis tools: LN TZ ZX LY. Wrote the paper: TX QB LN.