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Research Article

Chromatin Modification by PSC Occurs at One PSC per Nucleosome and Does Not Require the Acidic Patch of Histone H2A

  • Stanley M. Lo,

    Affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

    Current address: Program in Biological Sciences, Northwestern University Ventures in Biology Education and Searle Center for Teaching Excellence, Northwestern University, Evanston, Illinois, United States of America

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  • Kyle A. McElroy,

    Affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Nicole J. Francis mail

    francis@mcb.harvard.edu

    Affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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  • Published: October 11, 2012
  • DOI: 10.1371/journal.pone.0047162

About the Authors

Stanley M. Lo, Kyle A. McElroy, Nicole J. Francis
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: francis@mcb.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SML NJF. Performed the experiments: SML NJF. Analyzed the data: SML NJF. Contributed reagents/materials/analysis tools: SML KAM NJF. Wrote the paper: SML KAM NJF.