About the Authors

Richard E. Gilbert

Contributed equally to this work with: Richard E. Gilbert, Yuan Zhang

richard.gilbert@utoronto.ca (REG); dkelly@medstv.unimelb.edu.au (DJK)

Affiliation Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Ontario, Canada

Yuan Zhang

Contributed equally to this work with: Richard E. Gilbert, Yuan Zhang

Affiliation Department of Medicine, University of Melbourne, St. Vincent’s Hospital, Fitzroy, Victoria, Australia

Spencer J. Williams

Affiliation Bio21 Molecular Science and Biotechnology Institute, School of Chemistry, University of Melbourne, Parkville, Victoria, Australia

Steven C. Zammit

Affiliation Bio21 Molecular Science and Biotechnology Institute, School of Chemistry, University of Melbourne, Parkville, Victoria, Australia

David I. Stapleton

Affiliation Department of Physiology, University of Melbourne, Parkville, Victoria, Australia

Alison J. Cox

Affiliation Department of Medicine, University of Melbourne, St. Vincent’s Hospital, Fitzroy, Victoria, Australia

Henry Krum

Affiliation Centre of Cardiovascular Research and Education in Therapeutics, School of Public Health, Monash University, Melbourne, Australia

Robyn Langham

Affiliation Department of Medicine, University of Melbourne, St. Vincent’s Hospital, Fitzroy, Victoria, Australia

Darren J. Kelly

richard.gilbert@utoronto.ca (REG); dkelly@medstv.unimelb.edu.au (DJK)

Affiliations Department of Medicine, University of Melbourne, St. Vincent’s Hospital, Fitzroy, Victoria, Australia, Fibrotech Therapeutics Pty Ltd, Melbourne, Australia

Competing Interests

The authors have the following interests: Richard E. Gilbert, Spencer J. Williams, Steven C. Zammit, David Stapleton, Henry Krum and Darren J. Kelly are co-founders and stock holders of Fibrotech Therapeutics, one of the funders for this study. The FT011 drug used in this study was developed by Fibrotech Therapeutics, which is the patent owner. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors. Yuan Zhang, Alison J. Cox and Robyn Langham have no competing interests.

Author Contributions

Conceived and designed the experiments: DJK REG YZ. Performed the experiments: YZ AJC. Analyzed the data: YZ AJC DJK REG HK RL. Contributed reagents/materials/analysis tools: SJW SCZ DIS. Wrote the paper: REG YZ DJK.