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Research Article

Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens

  • Ayako Demachi-Okamura mail,

    ademachi@aichi-cc.jp (ADO); kkuzushi@aichi-cc.jp (KK)

    Affiliation: Division of Immunology, Aichi Cancer Center Research Institute, Nagoya, Japan

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  • Hiroki Torikai,

    Affiliation: Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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  • Yoshiki Akatsuka,

    Affiliations: Division of Immunology, Aichi Cancer Center Research Institute, Nagoya, Japan, Department of Hematology and Oncology, Fujita Health University, Toyoake, Japan

    X
  • Hiroyuki Miyoshi,

    Affiliation: Subteam for Manipulation of Cell Fate, RIKEN BioResource Center, Tsukuba, Japan

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  • Tamotsu Yoshimori,

    Affiliation: Department of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan

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  • Kiyotaka Kuzushima mail

    ademachi@aichi-cc.jp (ADO); kkuzushi@aichi-cc.jp (KK)

    Affiliations: Division of Immunology, Aichi Cancer Center Research Institute, Nagoya, Japan, Department of Cellular Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan

    X
  • Published: October 11, 2012
  • DOI: 10.1371/journal.pone.0047126

About the Authors

Ayako Demachi-Okamura, Yoshiki Akatsuka, Kiyotaka Kuzushima
Division of Immunology, Aichi Cancer Center Research Institute, Nagoya, Japan
Hiroki Torikai
Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Yoshiki Akatsuka
Department of Hematology and Oncology, Fujita Health University, Toyoake, Japan
Hiroyuki Miyoshi
Subteam for Manipulation of Cell Fate, RIKEN BioResource Center, Tsukuba, Japan
Tamotsu Yoshimori
Department of Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan
Kiyotaka Kuzushima
Department of Cellular Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ADO KK. Performed the experiments: ADO. Analyzed the data: ADO KK. Contributed reagents/materials/analysis tools: HT YA HM TY. Wrote the paper: ADO KK.