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Research Article

Role of Corticotropin-Releasing Factor (CRF) Receptor-1 on the Catecholaminergic Response to Morphine Withdrawal in the Nucleus Accumbens (NAc)

  • Pilar Almela,

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • Javier Navarro-Zaragoza,

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • Juan-Antonio García-Carmona,

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • Lucía Mora,

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • Juana Hidalgo,

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • María-Victoria Milanés,

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • María-Luisa Laorden mail

    laorden@um.es

    Affiliation: Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

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  • Published: October 10, 2012
  • DOI: 10.1371/journal.pone.0047089

About the Authors

Pilar Almela, Javier Navarro-Zaragoza, Juan-Antonio García-Carmona, Lucía Mora, Juana Hidalgo, María-Victoria Milanés, María-Luisa Laorden
Departamento de Farmacología, Facultad de Medicina, Universidad de Murcia, Murcia, Spain

Corresponding Author

Email: laorden@um.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MLL. Performed the experiments: JNZ JAGC LM JH. Analyzed the data: PA MVM MLL. Contributed reagents/materials/analysis tools: PA JAGC JH. Wrote the paper: PA MLL.