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Research Article

Pms2 Suppresses Large Expansions of the (GAA·TTC)n Sequence in Neuronal Tissues

  • Rebecka L. Bourn,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Irene De Biase,

    Affiliation: Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

    Current address: ARUP Laboratories, Department of Pathology, University of Utah, Salt Lake City, Utah, United States of America

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  • Ricardo Mouro Pinto,

    Affiliation: Biosciences Division, School of Health Sciences and Social Care, Brunel University, Uxbridge, United Kingdom

    Current address: Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Chiranjeevi Sandi,

    Affiliation: Biosciences Division, School of Health Sciences and Social Care, Brunel University, Uxbridge, United Kingdom

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  • Sahar Al-Mahdawi,

    Affiliation: Biosciences Division, School of Health Sciences and Social Care, Brunel University, Uxbridge, United Kingdom

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  • Mark A. Pook,

    Affiliation: Biosciences Division, School of Health Sciences and Social Care, Brunel University, Uxbridge, United Kingdom

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  • Sanjay I. Bidichandani mail

    Sanjay-Bidichandani@ouhsc.edu

    Affiliations: Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Published: October 11, 2012
  • DOI: 10.1371/journal.pone.0047085

About the Authors

Rebecka L. Bourn, Irene De Biase, Sanjay I. Bidichandani
Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
Sanjay I. Bidichandani
Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
Ricardo Mouro Pinto, Chiranjeevi Sandi, Sahar Al-Mahdawi, Mark A. Pook
Biosciences Division, School of Health Sciences and Social Care, Brunel University, Uxbridge, United Kingdom

Corresponding Author

Email: Sanjay-Bidichandani@ouhsc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RLB IDB MAP SIB. Performed the experiments: RLB IDB RMP CS SAM. Analyzed the data: RLB SIB. Contributed reagents/materials/analysis tools: MAP SIB. Wrote the paper: RLB SIB.