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Research Article

A Role for Nrf2 in Redox Signalling of the Invasive Extravillous Trophoblast in Severe Early Onset IUGR Associated with Preeclampsia

  • Nisreen Kweider mail,

    nkweider@ukaachen.de

    Affiliation: Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany

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  • Berthold Huppertz,

    Affiliation: Institute of Cell Biology, Histology and Embryology, Medical University of Graz, Graz, Austria

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  • Christoph Jan Wruck,

    Affiliation: Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany

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  • Rainer Beckmann,

    Affiliation: Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany

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  • Werner Rath,

    Affiliation: Department of Obstetrics and Gynecology, University Hospital of the RWTH, Aachen, Germany

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  • Thomas Pufe,

    Affiliation: Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany

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  • Mamed Kadyrov

    Affiliations: Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany, MEDIAN Kliniken, Baden-Wuerttemberg, Germany

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0047055

About the Authors

Nisreen Kweider, Christoph Jan Wruck, Rainer Beckmann, Thomas Pufe, Mamed Kadyrov
Department of Anatomy and Cell Biology, Medical Faculty, RWTH Aachen University, Aachen, Germany
Berthold Huppertz
Institute of Cell Biology, Histology and Embryology, Medical University of Graz, Graz, Austria
Werner Rath
Department of Obstetrics and Gynecology, University Hospital of the RWTH, Aachen, Germany
Mamed Kadyrov
MEDIAN Kliniken, Baden-Wuerttemberg, Germany

Corresponding Author

Email: nkweider@ukaachen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NK BH MK. Performed the experiments: NK RB MK. Analyzed the data: NK BH CJW WR TP MK. Contributed reagents/materials/analysis tools: NK BH CJW RB WR TP MK. Wrote the paper: NK BH MK.