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Research Article

Aging Contributes to Inflammation in Upper Extremity Tendons and Declines in Forelimb Agility in a Rat Model of Upper Extremity Overuse

  • David M. Kietrys,

    Affiliation: Department of Rehabilitation and Movement Sciences, University of Medicine and Dentistry of New Jersey, School of Health Related Professions, Stratford, New Jersey, United States of America

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  • Ann E. Barr-Gillespie,

    Affiliation: College of Health Professions, Pacific University, Hillsboro, Oregon, United States of America

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  • Mamta Amin,

    Affiliation: Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Christine K. Wade,

    Affiliation: Department of Physical Therapy, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

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  • Steve N. Popoff,

    Affiliation: Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Mary F. Barbe mail

    mary.barbe@temple.edu

    Affiliation: Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Published: October 03, 2012
  • DOI: 10.1371/journal.pone.0046954

About the Authors

David M. Kietrys
Department of Rehabilitation and Movement Sciences, University of Medicine and Dentistry of New Jersey, School of Health Related Professions, Stratford, New Jersey, United States of America
Ann E. Barr-Gillespie
College of Health Professions, Pacific University, Hillsboro, Oregon, United States of America
Mamta Amin, Steve N. Popoff, Mary F. Barbe
Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
Christine K. Wade
Department of Physical Therapy, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: mary.barbe@temple.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DMK MFB AEBG. Performed the experiments: DMK MFB AEBG MA CKW. Analyzed the data: DMK MFB AEBG MA. Contributed reagents/materials/analysis tools: SNP. Wrote the paper: DMK MFB AEBG CKW SNP.