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Research Article

Phase I Randomized Safety Study of Twice Daily Dosing of Acidform Vaginal Gel: Candidate Antimicrobial Contraceptive

  • Marla J. Keller mail,

    marla.keller@einstein.yu.edu

    Affiliations: Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America, Departments of Obstetrics and Gynecology and Women’s Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America

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  • Colleen A. Carpenter,

    Affiliation: Department of Pediatrics, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America

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  • Yungtai Lo,

    Affiliation: Departments of Epidemiology and Population Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America

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  • Mark H. Einstein,

    Affiliations: Departments of Obstetrics and Gynecology and Women’s Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America, Departments of Epidemiology and Population Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America

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  • Congzhou Liu,

    Affiliation: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • David N. Fredricks,

    Affiliation: Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Betsy C. Herold

    Affiliations: Departments of Obstetrics and Gynecology and Women’s Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America, Department of Pediatrics, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America, Departments of Microbiology and Immunology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America

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  • Published: October 08, 2012
  • DOI: 10.1371/journal.pone.0046901

About the Authors

Marla J. Keller
Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America
Marla J. Keller, Mark H. Einstein, Betsy C. Herold
Departments of Obstetrics and Gynecology and Women’s Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America
Colleen A. Carpenter, Betsy C. Herold
Department of Pediatrics, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America
Yungtai Lo, Mark H. Einstein
Departments of Epidemiology and Population Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America
Betsy C. Herold
Departments of Microbiology and Immunology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, New York, United States of America
Congzhou Liu, David N. Fredricks
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Corresponding Author

Email: marla.keller@einstein.yu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MJK MHE BCH DNF. Performed the experiments: CAC CL. Analyzed the data: MK MHE YL DNF BCH. Contributed reagents/materials/analysis tools: YL. Wrote the paper: MJK BCH.