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Research Article

Choriodecidual Infection Downregulates Angiogenesis and Morphogenesis Pathways in Fetal Lungs from Macaca Nemestrina

  • Ryan M. McAdams mail,

    adamsk@u.washington.edu

    Affiliation: Department of Pediatrics, University of Washington, Seattle, Washington, United States of America

    X
  • Jeroen Vanderhoeven,

    Affiliation: Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington, United States of America

    X
  • Richard P. Beyer,

    Affiliation: Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America

    X
  • Theo K. Bammler,

    Affiliation: Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America

    X
  • Federico M. Farin,

    Affiliation: Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America

    X
  • H. Denny Liggitt,

    Affiliation: Department of Comparative Medicine, University of Washington, Seattle, Washington, United States of America

    X
  • Raj P. Kapur,

    Affiliation: Department of Laboratories, Seattle Children’s, Seattle, Washington, United States of America

    X
  • Michael G. Gravett,

    Affiliations: Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington, United States of America, Global Alliance to Prevent Prematurity & Stillbirth, Seattle, Washington, United States of America

    X
  • Craig E. Rubens,

    Affiliations: Department of Pediatrics, University of Washington, Seattle, Washington, United States of America, Global Alliance to Prevent Prematurity & Stillbirth, Seattle, Washington, United States of America, Division of Infectious Disease, Seattle Children’s, Seattle, Washington, United States of America

    X
  • Kristina M. Adams Waldorf

    Affiliation: Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington, United States of America

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0046863

About the Authors

Ryan M. McAdams, Craig E. Rubens
Department of Pediatrics, University of Washington, Seattle, Washington, United States of America
Jeroen Vanderhoeven, Michael G. Gravett, Kristina M. Adams Waldorf
Department of Obstetrics & Gynecology, University of Washington, Seattle, Washington, United States of America
Richard P. Beyer, Theo K. Bammler, Federico M. Farin
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America
H. Denny Liggitt
Department of Comparative Medicine, University of Washington, Seattle, Washington, United States of America
Raj P. Kapur
Department of Laboratories, Seattle Children’s, Seattle, Washington, United States of America
Michael G. Gravett, Craig E. Rubens
Global Alliance to Prevent Prematurity & Stillbirth, Seattle, Washington, United States of America
Craig E. Rubens
Division of Infectious Disease, Seattle Children’s, Seattle, Washington, United States of America

Corresponding Author

Email: adamsk@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RMM KAW MGG CER. Performed the experiments: KAW. Analyzed the data: RPB TKB FF HDL JV RMM KAW RPK. Wrote the paper: RMM KAW JV TB RPK HDL.