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Research Article

Non-Diabetic Hyperglycemia Exacerbates Disease Severity in Mycobacterium tuberculosis Infected Guinea Pigs

  • Brendan K. Podell,

    Affiliation: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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  • David F. Ackart,

    Affiliation: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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  • Natalie M. Kirk,

    Affiliation: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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  • Sarah P. Eck,

    Affiliation: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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  • Christopher Bell,

    Affiliation: Department of Health and Exercise Science, College of Applied Human Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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  • Randall J. Basaraba mail

    randall.basaraba@colostate.edu

    Affiliation: Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America

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  • Published: October 04, 2012
  • DOI: 10.1371/journal.pone.0046824

About the Authors

Brendan K. Podell, David F. Ackart, Natalie M. Kirk, Sarah P. Eck, Randall J. Basaraba
Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America
Christopher Bell
Department of Health and Exercise Science, College of Applied Human Sciences, Colorado State University, Fort Collins, Colorado, United States of America

Corresponding Author

Email: randall.basaraba@colostate.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BKP DFA NMK SPE CB RJB. Performed the experiments: BKP DFA NMK SPE. Analyzed the data: BKP DFA CB RJB. Wrote the paper: BKP RJB.