About the Authors

Mikio C. Aoi

Affiliation Biomathematics Program, Department of Mathematics, North Carolina State University, Raleigh, North Carolina, United States of America

Kun Hu

Affiliation Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Men-Tzung Lo

Affiliation The Research Center for Adaptive Data Analysis/Center for Dynamical Biomarker and Translational Medicine, National Central University, Chungli, Taiwan, Republic of China

Magdy Selim

Affiliation Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

Mette S. Olufsen

Affiliation Biomathematics Program, Department of Mathematics, North Carolina State University, Raleigh, North Carolina, United States of America

Vera Novak

vnovak@bidmc.harvard.edu

Affiliation Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VN KH. Performed the experiments: VN. Analyzed the data: MCA KH VN. Contributed reagents/materials/analysis tools: KH MTL. Wrote the paper: MCA KH VN. Provided expert interpretation of data analysis and edited the manuscript: MS MSO.