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Research Article

Uterine NK Cells Are Critical in Shaping DC Immunogenic Functions Compatible with Pregnancy Progression

  • Irene Tirado González equal contributor,

    equal contributor Contributed equally to this work with: Irene Tirado González, Gabriela Barrientos

    Affiliation: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany

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  • Gabriela Barrientos equal contributor,

    equal contributor Contributed equally to this work with: Irene Tirado González, Gabriela Barrientos

    Affiliations: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany, Laboratorio de Fisiología Molecular Placentaria, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina

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  • Nancy Freitag,

    Affiliation: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany

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  • Teresa Otto,

    Affiliation: Institute of Molecular Biology, University Hospital, University Duisburg-Essen, Essen, Germany

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  • Victor L. J. L. Thijssen,

    Affiliation: Department of Radiotherapy, Angiogenesis Laboratory, VU University Medical Center, Amsterdam, The Netherlands

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  • Petra Moschansky,

    Affiliation: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany

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  • Petra von Kwiatkowski,

    Affiliation: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany

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  • Burghard F. Klapp,

    Affiliation: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany

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  • Elke Winterhager,

    Affiliation: Institute of Molecular Biology, University Hospital, University Duisburg-Essen, Essen, Germany

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  • Stefan Bauersachs,

    Affiliation: Chair for Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Munich, Germany

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  • Sandra M. Blois mail

    sandra.blois@charite.de

    Affiliation: Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany

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  • Published: October 08, 2012
  • DOI: 10.1371/journal.pone.0046755

About the Authors

Irene Tirado González, Gabriela Barrientos, Nancy Freitag, Petra Moschansky, Petra von Kwiatkowski, Burghard F. Klapp, Sandra M. Blois
Medicine University of Berlin, Charité Centre 12 Internal Medicine and Dermatology, Laboratory of Reproductive Medicine, Berlin, Germany
Gabriela Barrientos
Laboratorio de Fisiología Molecular Placentaria, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Teresa Otto, Elke Winterhager
Institute of Molecular Biology, University Hospital, University Duisburg-Essen, Essen, Germany
Victor L. J. L. Thijssen
Department of Radiotherapy, Angiogenesis Laboratory, VU University Medical Center, Amsterdam, The Netherlands
Stefan Bauersachs
Chair for Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Munich, Germany

Corresponding Author

Email: sandra.blois@charite.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SMB. Performed the experiments: ITG GB NF TO VLJLT PM PVK SMB. Analyzed the data: ITG GB NF SB. Contributed reagents/materials/analysis tools: BFK EW. Wrote the paper: GB SMB.