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Research Article

Regulation of NF-κB Activation through a Novel PI-3K-Independent and PKA/Akt-Dependent Pathway in Human Umbilical Vein Endothelial Cells

  • Sakshi Balwani,

    Affiliation: Molecular Immunogenetics Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

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  • Rituparna Chaudhuri,

    Affiliation: Molecular Immunogenetics Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

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  • Debkumar Nandi,

    Affiliation: Department of Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata, India

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  • Parasuraman Jaisankar,

    Affiliation: Department of Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata, India

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  • Anurag Agrawal,

    Affiliation: Molecular Immunogenetics Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

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  • Balaram Ghosh mail

    bghosh@igib.res.in

    Affiliation: Molecular Immunogenetics Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India

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  • Published: October 05, 2012
  • DOI: 10.1371/journal.pone.0046528

About the Authors

Sakshi Balwani, Rituparna Chaudhuri, Anurag Agrawal, Balaram Ghosh
Molecular Immunogenetics Laboratory, CSIR-Institute of Genomics and Integrative Biology, Delhi, India
Debkumar Nandi, Parasuraman Jaisankar
Department of Medicinal Chemistry, CSIR-Indian Institute of Chemical Biology, Jadavpur, Kolkata, India

Corresponding Author

Email: bghosh@igib.res.in

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SB BG PJ. Performed the experiments: SB RC DN. Analyzed the data: SB BG AA PJ. Contributed reagents/materials/analysis tools: BG SB RC PJ. Wrote the paper: SB PJ AA BG.