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Research Article

Postconditioning with Inhaled Carbon Monoxide Counteracts Apoptosis and Neuroinflammation in the Ischemic Rat Retina

  • Nils Schallner mail,

    nils.schallner@uniklinik-freiburg.de

    Affiliation: Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany

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  • Matthias Fuchs,

    Affiliation: Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany

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  • Christian I. Schwer,

    Affiliation: Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany

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  • Torsten Loop,

    Affiliation: Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany

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  • Hartmut Buerkle,

    Affiliation: Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany

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  • Wolf Alexander Lagrèze,

    Affiliation: University Eye Hospital, University Medical Center, Freiburg, Germany

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  • Christian van Oterendorp,

    Affiliation: University Eye Hospital, University Medical Center, Freiburg, Germany

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  • Julia Biermann equal contributor,

    equal contributor Contributed equally to this work with: Julia Biermann, Ulrich Goebel

    Affiliation: University Eye Hospital, University Medical Center, Freiburg, Germany

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  • Ulrich Goebel equal contributor

    equal contributor Contributed equally to this work with: Julia Biermann, Ulrich Goebel

    Affiliation: Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany

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  • Published: September 28, 2012
  • DOI: 10.1371/journal.pone.0046479

About the Authors

Nils Schallner, Matthias Fuchs, Christian I. Schwer, Torsten Loop, Hartmut Buerkle, Ulrich Goebel
Department of Anesthesiology and Critical Care Medicine, University Medical Center Freiburg im Breisgau, Germany
Wolf Alexander Lagrèze, Christian van Oterendorp, Julia Biermann
University Eye Hospital, University Medical Center, Freiburg, Germany

Corresponding Author

Email: nils.schallner@uniklinik-freiburg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NS JB UG. Performed the experiments: NS MF CS CvO. Analyzed the data: NS JB UG. Contributed reagents/materials/analysis tools: TL HB WL. Wrote the paper: NS TL UG.