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Research Article

Maternal Transmission Effect of a PDGF-C SNP on Nonsyndromic Cleft Lip with or without Palate from a Chinese Population

  • Di Wu equal contributor,

    equal contributor Contributed equally to this work with: Di Wu, Mei Wang

    Affiliation: Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

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  • Mei Wang equal contributor,

    equal contributor Contributed equally to this work with: Di Wu, Mei Wang

    Affiliations: Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China, Graduate University of Chinese Academy of Sciences, Beijing, People's Republic of China

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  • Xingang Wang,

    Affiliation: Department of Stomatology, Beijing Children Hospital Affiliated to Capital University of Medical Sciences, Beijing, People's Republic of China

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  • Ningbei Yin,

    Affiliation: Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

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  • Tao Song,

    Affiliation: Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

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  • Haidong Li,

    Affiliation: Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China

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  • Feng Zhang,

    Affiliation: Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China

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  • Yongbiao Zhang,

    Affiliation: Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China

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  • Zhenqing Ye,

    Affiliation: Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China

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  • Jun Yu,

    Affiliation: Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China

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  • Duen-Mei Wang mail,

    dmwang@usa.net (DMW); zhaozhenmin0098@gmail.com (ZZ)

    Affiliation: Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China

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  • Zhenmin Zhao mail

    dmwang@usa.net (DMW); zhaozhenmin0098@gmail.com (ZZ)

    Affiliations: Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China, People's Hospital of Jincheng City, Jincheng, Shanxi, People's Republic of China

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  • Published: September 28, 2012
  • DOI: 10.1371/journal.pone.0046477

About the Authors

Di Wu, Ningbei Yin, Tao Song, Haidong Li, Zhenmin Zhao
Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China
Mei Wang, Feng Zhang, Yongbiao Zhang, Zhenqing Ye, Jun Yu, Duen-Mei Wang
Chinese Academy of Sciences Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China
Mei Wang
Graduate University of Chinese Academy of Sciences, Beijing, People's Republic of China
Xingang Wang
Department of Stomatology, Beijing Children Hospital Affiliated to Capital University of Medical Sciences, Beijing, People's Republic of China
Zhenmin Zhao
People's Hospital of Jincheng City, Jincheng, Shanxi, People's Republic of China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZZ DMW JY. Performed the experiments: DW MW FZ. Analyzed the data: DW MW YZ ZY. Contributed reagents/materials/analysis tools: XW NY TS HL. Wrote the paper: MW DW DMW.