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Research Article

Genome-Wide Analysis of Androgen Receptor Targets Reveals COUP-TF1 as a Novel Player in Human Prostate Cancer

  • Ruth Perets,

    Affiliations: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel, Division of Oncology, Rambam Health Care Campus, Haifa, Israel

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  • Tommy Kaplan,

    Affiliations: Department of Molecular and Cell Biology, California Institute of Quantitative Biosciences, University of California, Berkeley, California, United States of America, School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel

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  • Ilan Stein,

    Affiliation: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Guy Hidas,

    Affiliations: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel, Department of Urology, The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Shay Tayeb,

    Affiliation: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Eti Avraham,

    Affiliation: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Yinon Ben-Neriah,

    Affiliation: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Itamar Simon,

    Affiliation: Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Eli Pikarsky mail

    Peli@hadassah.org.il

    Affiliation: Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel

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  • Published: October 04, 2012
  • DOI: 10.1371/journal.pone.0046467

About the Authors

Ruth Perets, Ilan Stein, Guy Hidas, Shay Tayeb, Eti Avraham, Yinon Ben-Neriah, Eli Pikarsky
Department of Pathology and Lautenberg center for immunology, IMRIC, The Hebrew University-Hadassah Medical School, Jerusalem, Israel
Guy Hidas
Department of Urology, The Hebrew University-Hadassah Medical School, Jerusalem, Israel
Itamar Simon
Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel
Tommy Kaplan
Department of Molecular and Cell Biology, California Institute of Quantitative Biosciences, University of California, Berkeley, California, United States of America
Tommy Kaplan
School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel
Ruth Perets
Division of Oncology, Rambam Health Care Campus, Haifa, Israel

Corresponding Author

Email: Peli@hadassah.org.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RP TK I. Stein I. Simon YBN EP. Performed the experiments: RP ST EA. Analyzed the data: RP TK I. Stein I. Simon EP. Contributed reagents/materials/analysis tools: GH. Wrote the paper: RP TK I. Simon EP. Bioinformatical analysis: TK.