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Research Article

Gene-Gene Interaction and Functional Impact of Polymorphisms on Innate Immune Genes in Controlling Plasmodium falciparum Blood Infection Level

  • Madhumita Basu,

    Affiliation: Department of Biochemistry, University of Calcutta, Kolkata, West Bengal, India

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  • Tania Das,

    Affiliation: Cancer & Cell Biology Division, Indian Institute of Chemical Biology, Kolkata, West Bengal, India

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  • Alip Ghosh,

    Affiliation: Centre for Liver Research, The Institute of Post-Graduate Medical Education & Research, Kolkata, West Bengal, India

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  • Subhadipa Majumder,

    Affiliation: Department of Biochemistry, University of Calcutta, Kolkata, West Bengal, India

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  • Ardhendu Kumar Maji,

    Affiliation: Department of Protozoology, The Calcutta School of Tropical Medicine, Kolkata, West Bengal, India

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  • Sumana Datta Kanjilal,

    Affiliation: Department of Pediatric Medicine, Calcutta National Medical College, Kolkata, West Bengal, India

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  • Indranil Mukhopadhyay,

    Affiliation: Human Genetics Unit, Indian Statistical Institute, Kolkata, West Bengal, India

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  • Susanta Roychowdhury,

    Affiliation: Cancer & Cell Biology Division, Indian Institute of Chemical Biology, Kolkata, West Bengal, India

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  • Soma Banerjee,

    Affiliation: Centre for Liver Research, The Institute of Post-Graduate Medical Education & Research, Kolkata, West Bengal, India

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  • Sanghamitra Sengupta mail

    sanghamitrasg@yahoo.com

    Affiliation: Department of Biochemistry, University of Calcutta, Kolkata, West Bengal, India

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  • Published: October 12, 2012
  • DOI: 10.1371/journal.pone.0046441

About the Authors

Madhumita Basu, Subhadipa Majumder, Sanghamitra Sengupta
Department of Biochemistry, University of Calcutta, Kolkata, West Bengal, India
Tania Das, Susanta Roychowdhury
Cancer & Cell Biology Division, Indian Institute of Chemical Biology, Kolkata, West Bengal, India
Alip Ghosh, Soma Banerjee
Centre for Liver Research, The Institute of Post-Graduate Medical Education & Research, Kolkata, West Bengal, India
Ardhendu Kumar Maji
Department of Protozoology, The Calcutta School of Tropical Medicine, Kolkata, West Bengal, India
Sumana Datta Kanjilal
Department of Pediatric Medicine, Calcutta National Medical College, Kolkata, West Bengal, India
Indranil Mukhopadhyay
Human Genetics Unit, Indian Statistical Institute, Kolkata, West Bengal, India

Corresponding Author

Email: sanghamitrasg@yahoo.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS MB. Performed the experiments: MB TD AG SM. Analyzed the data: MB SS. Contributed reagents/materials/analysis tools: SR AKM SDK. Wrote the paper: SS MB. Guided the MDR analysis: IM. Provided cell line and vectors: SB.